At what point in the investigation is?

The clinical research program of cell therapy in patients with spinal cord injury began in the Hospital Universitario Puerta de Hierro-Majadahonda in March 2013 and have now been treated and 12 patients with complete spinal cord injury and chronically established, through the first clinical trial of this nature adopted in Spain by the Spanish Agency of Medicines. The results of this first trial will be announced later this year, when all patients have completed the set-up time in the study protocol. A second clinical trial, dirigido a pacientes con lesiones medulares incompletas se encuentra actualmente en fase de ejecución y sus resultados se podrán hacer públicos a finales del próximo año.

What is work or technical?

It involves the application of a cell therapy medicinal, manufactured in Cell Production Room Service Neurosurgery Hospital Puerta de Hierro, and whose active component are stem cells from the patient's own bone marrow. Cells are implanted in the injured spinal cord of patients, mediante una intervención quirúrgica compleja y con una técnica adaptada a las características de las diferentes lesiones de los pacientes.

How financed research?

To set up this program, the Puerta de Hierro Hospital received ago 3 years a grant from the Association of SCI APINME, enabling install the necessary room Cell Production for cell cultures. This room is the first of our country designed specifically for cell therapy treatments for neurological and has a leading technology in this field. The first two studies in patients have been conducted through grants from government agencies, specifically the Ministry of Health, and we are already preparing a third trial funded by the Instituto de Salud Carlos III, through the Health Research Fund. A program of this type, however, It is extraordinarily expensive, by the high costs of maintaining the Living Cell Production, recruitment, cleaning costs, validating devices, etc., making it necessary to resort to additional subsidies, which for now are being achieved through various foundations, as the Foundation Rafael del Pino, Mapfre Foundation, Foundation SERMs, etc., working with this project, Nonprofit. Undoubtedly, the maintenance of this program is difficult, in the current state of economic and because of these technical difficulties are still undergoing clinical investigation, and therefore, not covered by health care resources of our hospitals. Our immediate goal, therefore, is the consolidation of these treatments, showing a clear improvement in the quality of life of patients, and can be incorporated as soon as possible, a la cartera de servicios de nuestra Sanidad Pública.

On the other hand, se trata este programa socio sanitario de gran impacto por su innovación y por su aplicación a pacientes con grave discapacidad neurológica tras secuelas de un daño medular adquirido.

It is based on more than 20 years of research entirely in Spain, and has allowed the development of the first human cell therapy registered in our country, Spanish Agency for Medicines and Health Products(Competent Authority), con indicación terapéutica “para lesiones traumáticas de la medula espinal”.

The research is very expensive and to try to achieve those revenues needed for association studies proinvestigación for the repair of spinal cord injury was created (APINME) and their website is www.apinme.org.

Se puede decir que se puede ser optimista y esperanzador.

By Jorge Moreno. Source: http://www.elpollourbano.es/sin-barreras/2015/02/el-neurocirujano-doctor-vaquero-da-un-paso-mas-en-la-recuperacion-de-lesionados-medulares-un-importantisimo-avance-medico/

PREMIO I D

Paraplegic Cell Therapy in Patients with Large Unit,
Jesus Mercedes Zurita and Vaquero, Researchers at University Hospital Puerta de Hierro-Majadahonda

http://www.investigacionpuertadehierr…
http://fundacioncaser.es

Traumatic spinal cord injury is one of the greatest medical and social problems, sin que existan terapias efectivas capaces de restablecer las secuelas neurológicas que se originan como consecuencia del mismo.

El galardón reconoce la trayectoria investigadora de los premiados en el campo de la terapia celular aplicada al tratamiento de graves secuelas neurológicas tras daño medular adquirido.

Se trata de un programa socio-sanitario de gran impacto por su innovación y por su aplicación a pacientes con grave discapacidad neurológica tras secuelas de un daño medular adquirido.

It is based on more than 20 years of research entirely in Spain, and has allowed the development of the first human cell therapy registered in our country, Spanish Agency for Medicines and Health Products (Competent Authority), with therapeutic indications “traumatic injury to the spinal cord”.

Now, following the development of this research, has initiated a program established Cell Therapy Neurological University Hospital Puerta de Hierro-Majadahonda, que contempla la realización de ensayos clínicos no comerciales para el tratamiento de pacientes con lesiones adquiridas del sistema Nervioso.

This is a pioneering program in Spain, para la búsqueda de nuevos tratamientos capaces de paliar las graves secuelas de la discapacidad neurológica y causantes de grave discapacidad.
El principal ámbito de aplicación de estas nuevas técnicas son pacientes con grave dependencia secundaria a una lesión medular traumática.

In Spain the prevalence of traumatic spinal cord injury is estimated to exceed the 30.000 patients, with an incidence of between 800 and 1.000 nuevos casos cada año.

El Dr. Jesus Vaquero, Professor of Neurosurgery at the Autonomous University of Madrid and Director of the Neuroscience Research Unit of the Hospital Universitario Puerta de Hierro- Majadahonda and Dr.. Mercedes Zurita, Investigadora del Servicio Madrileño de Salud y Directora Técnica de la Sala de Producción Celular de la UINC del Hospital Universitario Puerta de Hierro-Majadahonda han sido los ganadores por el Programa de Terapia Celular en pacientes Parapléjicos con Gran Dependencia.

Source: https://www.youtube.com/watch?v=5W5ak0lXAAA

In the following link you can see the intervention of Dr. D. Jesus Vaquero Crespo in Scientific Special Session on World Day of Persons with Disabilities, llevada a cabo en la Real Academia Nacional de Medicina.

Him, el Dr. Cowboy explains ongoing research and current developments in a scientific session 30 minutos.

Video